28 Oct 2024        11:40:57 am

Biology

BPaLM Regimen

Tags : BPaLM Regimen

Topic: Disease Treatment

Why in the news?

• The Union Health Ministry approved the introduction of a new treatment regimen for multidrug-resistant tuberculosis in India. 
• The BPaLM regimen has proven to be a safe, more effective and quicker treatment option than the previous multidrug-resistant tuberculosis (MDR-TB) treatment procedure.

Source: The Hindu 

About BPaLM Regimen:

• It is a new treatment regimen against multi-drug-resistant tuberculosis (MDR-TB).
• It was introduced by the Union Health Ministry under its National TB Elimination Program (NTEP).
• It combines four drugs i.e. Bedaquiline, Pretomanid, Linezolid, and optionally Moxifloxacin.
• It includes a new anti-TB drug called Pretomanid, which was earlier approved and licensed for use in India by the Central Drugs Standard Control Organization (CDSCO).
• Efficacy:
  • It is a safer and more effective treatment option compared to traditional MDR-TB treatments.
  • It is an all-oral regimen with a low overall pill burden, which makes it patient-friendly.
  • It can cure drug-resistant TB in just six months, compared to the previous treatment duration of up to 20 months, and is associated with fewer side effects.

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